Drug-Resistant TB

Testing and Treatment of Latent Tuberculosis Infection in the United States: A Clinical Guide for Health Care Providers and Public Health Programs: Section 9: Considerations for Specific Populations: Contacts to Persons with Infectious Drug-Resistant TB

This subsection of the Clinical Guide explains treatment of LTBI in contacts of persons with infectious isoniazid-resistant TB and multidrug-resistant TB. Note that expert consultation should be obtained for these patients. National Society of Tuberculosis Clinicians and National Tuberculosis Coalition of America, 2025: 76-77. 

Drug-Resistant TB: A Tool for TB Nurse Case Management

This 12-page booklet defines DR-TB, notes which patients are most at risk, explains diagnosis, outlines treatment, describes treatment options, explains monitoring for side effects and adverse events. Heartland National TB Center, 2023.

Characteristics of Second-Line Drugs for MDR-TB (Revised)

This one-page flow diagram was developed for use by clinicians and healthcare providers. Heartland National TB Center, 2023.

Drug-Resistant TB: A Survival Guide for Clinicians, Third Edition

The guide’s information and tools are designed for healthcare providers who participate in the management of patients with drug-resistant TB. Ten chapters cover major topics pertaining to epidemiology, diagnosis, laboratory issues, treatment, medications, pediatrics, co-morbidities and special situations, monitoring and case management, adverse reactions, and treatment of contacts. Curry International TB Center, 2022.

Basics of MDR-TB Clinical Care

This series of short, online video lectures covers major topics in MDR-TB: epidemiology, diagnosis, treatment regimens, side effects, and nurse case management. California Department of Public Health and Curry International TB Center, 2017-2020.

Nursing Guide for Managing Side Effects to Drug-Resistant TB Treatment

The guide is a reference and job aid to assist nurses to quickly identify symptoms that may indicate a side effect related to drug-resistant TB treatment or antiretroviral medication; assess for severity as well as other potential contributors; and intervene appropriately to minimize patient discomfort, reduce side effect progression, and ultimately support successful treatment completion. Curry International TB Center and International Council of Nurses, 2018.

Outpatient Infusion Therapy for Multidrug Resistant TB: A Practical Guide

This resource provides practical guidance on how to organize a clinic to provide outpatient infusion therapy for MDR-TB. New Jersey Medical School National TB Center, 2004.