Testing and Diagnosis

For TB diagnosis and treatment in special situations, such as pediatric TB or patients with HIV, liver disease, or other comorbidities, also check for resources under Special Situations.

Core Curriculum on Tuberculosis: What the Clinician Should Know, 7th Edition: Chapter 2 Testing for Tuberculosis Infection and Lesson 3 Diagnosis of Tuberculosis Disease

This chapter explains testing for TB infection (or latent TB infection [LTBI]) and TB disease. Centers for Disease Control and Prevention, 2021.

Testing and Treatment of Latent Tuberculosis Infection in the United States: A Clinical Guide for Health Care Providers and Public Health Programs: Section 1: Immunologic Tests for Tuberculosis Infection and Section 3 Pretreatment Clinical Evaluation

These sections of the Clinical Guide explain LTBI testing and diagnosis. National Society of Tuberculosis Clinicians and National Tuberculosis Coalition of America, 2025.

World Atlas of BCG Policies and Practices

This interactive map provides detailed information on current and past BCG vaccination policies and practices for over 200 countries. McGill University, 2020.

Online TST/IGRA Interpreter

This tool estimates the risk of active tuberculosis for an individual with a tuberculin skin test reaction of ≥5mm, based on his/her clinical profile. It is intended for adults tested with standard tuberculin (5 TU PPDS, or 2 TU RT-23) and/or a commercial Interferon Gamma release assay (IGRA). McGill University.

From TSTin3D to TSTin4D: Enhancing Tuberculosis Preventive Treatment Decisions with Risk-Benefit Analyses

In this 1-hour webinar, Dick Menzies and Lisa Chen highlight the updates made to the Online TST/IGRA Interpreter and demonstrate how to use this tool to support preventive treatment decisions for TB. Curry International TB Center, 2025.

Sputum Collection Videos

Videos in English, Spanish, and Chuukese explain home sputum collection and sputum induction works. Rutgers New Jersey Medical School Global TB Institute.

A Clinician’s Guide to the TB Laboratory

The 98-page guide provides basic information on the use of the public health and clinical laboratories in the diagnosis and monitoring of patients with LTBI and TB disease. Heartland National TB Center, 2021.

Radiographic Manifestations of TB: A Primer for Clinicians, Second Edition

Using a self-study format, this publication presents the physical principles of plain chest radiography. Topics include basic chest radiograph interpretation, radiographic manifestations of TB, and clinical cases. Curry International TB Center, 2020.

TB Radiology Practice Cases

These brief, interactive self-study case studies allow clinicians to practice locating areas of radiographic abnormalities using real-life clinical scenarios. Firland Northwest TB Center and Curry International TB Center, 2014.

Basic Chest Radiology for the TB Clinician

A 54-minute self-study module presents the basics of how to read chest radiographs, covering basic anatomy, disease patterns, and tuberculosis specific presentations. Curry International TB Center, 2011.

TB Radiology Image Library

This open-access resource library contains radiographic images of TB that are free to download and share for non-commercial educational purposes. Firland Northwest TB Center and Curry International TB Center.

Mental Health Assessment Tool

This mental health assessment is to provide the clinician with a quick screening tool for use with their TB patients in order to identify possible areas of concern or a need for referral to a mental health professional. It contains a series of questionnaires and observations to be documented during the patient’s medical evaluation and history-taking in order to highlight significant issues that should be addressed by TB program staff (or referral). Heartland National TB Center, 2021.